Awareness of Aspirin’s Dual Role as an Anti-cancer Agent and Anti- thrombotic Agent and its Association with Medication Adherence to Low-Dose Aspirin: A Cross-Sectional Study

Authors

• Hadhyah N. Alabdali, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
• Sarah S. Al- Harbi, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
• Layan Z. Sharalahi, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
• Yosra Z. Alhindi, Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi ArabiaFollow

Keywords

Aspirin; Anticancer; Antithrombotic, Makkah, Adherence.

Document Type

Research Article

Abstract

Background: Aspirin is known to be an effective antithrombotic agent. Multiple studies have been studying its effect on cancer as colorectal cancer. Aim: This study aimed to measure the Awareness of Aspirin's Dual Function as an Anti-Cancer Agent and Anti-Thrombotic among Residents of the Makkah region in the Kingdom of Saudi Arabia. Methods: A cross-sectional study was conducted involving 490 participants from the Makkah region. Data collection was achieved through a self-reported online questionnaire and distributed via social media platforms from period of November 2024 until January 2025. Results: Over 340 of the participants in this research have bachelor's degrees. However, while investigating awareness regarding the preventative effect of aspirin's dual role, only 8.4% were aware. Moreover, in terms of assessing the adherence level, we only included 306 (62.4%) of the participants who reported taking aspirin. The majority of them showed low adherence levels. Conclusion: This study reveals a lack of awareness regarding of the knowledge abouts Aspirin as an Anti-Cancer and Anti-Thrombotic Agent among the residents of Makkah region, which appears to have an effect on medication adherence. Awareness promotion is essential to enhance public health outcomes.

Recommended Citation

Alabdali, Hadhyah N.; Al- Harbi, Sarah S.; Sharalahi, Layan Z.; and Alhindi, Yosra Z. (2025) "Awareness of Aspirin’s Dual Role as an Anti-cancer Agent and Anti- thrombotic Agent and its Association with Medication Adherence to Low-Dose Aspirin: A Cross-Sectional Study," Saudi Toxicology Journal: Vol. 2: Iss. 2, Article 2.
DOI: https://doi.org/10.70957/uqu.edu.sa/s.toxicology.s/stj.2025.2.2
Available at: https://stj.researchcommons.org/journal/vol2/iss2/2

DOI

https://doi.org/10.70957/uqu.edu.sa/s.toxicology.s/stj.2025.2.2